Fuckscuse me
When you are severely done with the ignorance of a person, and are in disbelief of the shit that just came out of their mouth. Use "fuckscuse me" to elaborate on the term "excuse me", with a hint of sass, as well as saying "fuck you" in a not so subtle tone.
Ben: "You're ugly."
Felicia: "Fuckscuse me?!"
Felicia: "Fuckscuse me?!"