Genitanglia

A paralyzing condition in which the subject's (male) undergarments become inexplicably entwined with his genitals (usually, but not limited to "the bag") usually beginning with mild discomfort but if left unchecked will become increasingly disabling and in some cases crippling.

Examples of such issues occur when said undergarments are worn to bed, after perspiration, or whilst driving on a hot day.