getting on my nerves
When someone's being annoying and you're wishing they'd stop.
While travelling:
son: "are we there yet?"
father: "no"
son: "are we there yet?"
father: "you're getting on my nerves"
son: "are we there yet?"
father: "no"
son: "are we there yet?"
father: "you're getting on my nerves"
get on my last nerve
Means when you are ready to lose your temper
You are about to get on my last nerve if you keep asking stupid questions.