HYPMSC
A combined acronym referring to the universities: Harvard-Yale-Princeton-Massachusetts Institute of Technology--Stanford-Caltech. Used by major nerds. Can be pronounced "Hype-misk."
Person A: Do you think your brother will get into HYPMSC?
Person B: Naw, maybe top 5-10, but not those.
Person B: Naw, maybe top 5-10, but not those.