Are you tighter then a 5th grader
In relation to the game show Are You Smarter Then A 5th Grader, it is asking whether a female's vagina is tight or loose. Or, whether she is a good girl or a dirty tea-bagging whore.
I saw a hottie from across the room but she looked like she'd been passed around, so before I sealed the deal I asked her, "Girl I got to know, are you tighter then a 5th grader?"