Jizzmata
Jizzmata are bodily marks of semen in locations corresponding to the crucifixion wounds of Jesus. In some rare cases they are found on the anus. The causes of Jizzmata may vary from case to case but almost always appear while sleeping. Most Jizzmatics are female.
At the age of 20, Zoe started to display signs of Jizzmata on her forehead, hands and anus. Supernatural causes have never been disproven but many believe it to be a hoax by her boyfriend.