karmastrophe
The catastrophic consequences of wrongdoing or bad decisions coming together in a symphony of bad luck, pain and suffering beyond the worst nightmares of the offender. Also, often referred to as "Karmageddon".
"That guy has screwed over so many people, he's headed for a karmastrophe, for sure!"
"Yep. KARMAGEDDON!"
"Yep. KARMAGEDDON!"