Morris-Davies Syndrome
A condition where a medical doctor experiences rectal prolapse that worsens eventually leading to their anus enveloping their whole body. This is particularly prevalent in Shanghai, China.
"You have back pain? I don't care, I'm going to nullify all of your refills for your pain medicine because I can." The doctor then turns into one gigantic anus and is inflicted with Morris-Davies Syndrome. No known treatment is available.