barbitchuate
Pharmaceuticals that cause people to be bitchy, arrogant, snobbish, stuck-up and just plain rude. This may be either an intended effect of a medication or a side effect.
What the hell is the problem with that blonde? Is this how she usually behaves or is she on some kind of barbitchuate? Her doctor needs to stop prescribing those to her. She's intolerable to be around.