Run my shit
to do what needs to be done or to take care of business.
Person one: "What are you gunna do today?"
Person two: "I gotta run my shit, bitch."
Person two: "I gotta run my shit, bitch."
run me my shits
Basically when two people are having a confrontation and one of them wants to fight, they will say "run me my shits". It's a long way around just saying "fight me right now".
Bob fucks Jim's girlfriend*
Bob: Bro I didn't mean to fuck her
Jim: Run me my shits
They proceed to fight*
Bob: Bro I didn't mean to fuck her
Jim: Run me my shits
They proceed to fight*