soul cancer
When a certain set of circumstances bogs you down and makes you depressed or leaves you wanting to give up. A feeling of immense hopelessness or depression.
This town is starting to give me soul cancer.
soul cancer
When something makes you cringe so bad it gives you stage 4 soul cancer.
"Your post gave me soul cancer"
or
"Your post gave me stage 4 soul cancer"
or
"Your post gave me stage 4 soul cancer"