Biggy Smalls Syndrome
A female consisting of a fat ass and no tits.
"Hey Ricky, dating that chick that has Biggy Smalls Syndrome will ultimately lead to your downfall."
Biggie Smalls syndrome
When one womans breast is larger than the other.
Yo mama got one big titty and one little titty, they call the bitch biggie smalls! - Biggie Smalls syndrome
Biggie Smalls Syndrome
When a woman has one breast larger than the other.
Amy is getting a boob job to cure her biggie smalls syndrome.