the dave chappelle/rick james effect
It happens whenever something funny is presented, then wholly gobbled up by the media and public, excreted into senseless dreck, and then whatever originality and humor was left in the original source of material, has been thouroughly raped into bleeding submission.
Eg; whenever someone says "I'm Rick James B*tch", or anyone makes a quote from Napoleon Dynamite. Particularly "Gosh", or something along those lines.