BrainFallOutitis
A serious condition in which one's brain falls directly out of their skull, resulting in instant death and messy carpets. The primary cause is a deficit of squeezing the butts of petite females. As of this time there is no known cure, despite efforts to attempt using an ice cream scoop to plop the brains back into the skull.
"Man it sure is a shame that Trevor died of BrainFallOutitis. If only he'd had a butt to squeeze."