lose at life
To make a social blunder so bad, you drive away your friends, lose a great opportunity, become infamous, or an otherwise unpleasant consequence of a seemingly in consequent action
Person: I thought he would accept me, so I told him I want to create weapons of mass destruction when I grow up. Now, he's disturbed by me.
Person's mind: You lose at life.
Person's mind: You lose at life.
lose life
An insult. Similar to telling someone to Get lost, Get real, stop being silly, that's rediculous etc...
Lose life Brad, I'm not going on a date with you!